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Four Probes Add CPL and POF to Spectrometers

Booth 1425. Four probes provide complementary information with polarization of fluorescence (POF) and circularly polarized luminescence (CPL), offering insights into the structure, interactions and environment of an emitting molecule. A new, proprietary, upgrade accessory adds both CPL and POF to any circular dichroism (CD) or fluorescence spectrometer for kinetic or steady-state readings. In addition, single purpose models are also available. POF and CPL are less-utilized, highly sensitive probes of molecular interactions, such as protein folding and secondary structure formation. Whereas CD involves the ground state of a chiral molecule, CPL is emitted by a fluorophore if the excited state of the emitting species is chiral. Fluorescence offers insights into the environment surrounding the emitting molecule; anisotropy (POF) is sensitive to rotational motion of the fluorescent probe.
OLIS
130 Conway Drive
Bogart, GA, 30622





















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